Anti-Aging and Skin Care Benefits of Non-Denatured Dill Seed Extract
Authors:
Dr. Razak Clinical Pharmacy Scientist
Bill Soukup formulator
Article at a Glance·Elastin and collagens are the primary proteins responsible for maintaining the structure and elasticity of the skin as well as keeping skin firm and supple. ·Natural extracts like dill seed extract, work in two ways, either they stop the destruction of elastin and collagen, or they help in the increased production of both essential skin care proteins. ·Dill seed extract stimulates elastin and collagen synthesis by activating dermal fibroblasts. ·Dill seed extract also increases the production of the precursor of elastin, tropoelastin. ·Dill seed extract helps increase expression of Lysyl oxidase-like enzymes in skin that generates elastin and help rebuild skin’s structural integrity. ·Over 900 extracts were tested and, dill seed was one of a few that contained the Lysyl oxidase-like enzyme so beneficial to elastin. ·Dill seed oil, commonly and incorrectly referred to in blogs, does not contain the Lysyl oxidase enzyme that stimulates growth. Oils do not contain enzymes which are proteins. ·Denatured dill seed extracts will not contain the Lysyl oxidase enzyme. ·Several scientific studies have shown that topical application of formulas with dill may help to reinforce skin elasticity and firmness, thus improving the overall appearance of skin. As a result, the benefits of dill extract are often infused in anti-aging skincare formulas. ·Due to the anti-microbial activity, dill destroys the micro-organism and thus prevents the destruction of beauty proteins. |
Dill Seed Extract Stimulates Elastin And Collagen
Elastin and collagens are the primary proteins responsible for maintaining the structure and elasticity of the skin as well as keeping skin firm and supple. Both proteins decrease with age, leading to the shrinkage and wrinkles of the skin.
Natural extracts like non-denatured dill seed extract, work in two ways, either they stop the destruction of elastin and collagen, or they help in the increased production of both essential skincare proteins.
Dill seed extract stimulates elastin and collagen synthesis by activating dermal fibroblasts according to a 2006 study in Experimental Dermatology. Fibroblasts synthesize collagen, elastin, and keratin in the dermis. They assist in wound healing and the prevention of skin aging.
Note:
- Dill seed extract is different from dill seed oil. Most research was conducted on dill seed extract. Many bloggers incorrectly refer to dill seed oil for elastin and collagen regeneration. Dill seed oil does not contain the Lysyl oxidase enzyme that stimulates collagen and elastin growth. Oils do not contain enzymes which are proteins.
- Denatured dill seed extracts will not contain the Lysyl oxidase enzyme. Heat at 106° Fahrenheit, 40° Celsius breaks down proteins. Alcohol at any level denatures proteins.
Dill seed extract also increases the production of the precursor of elastin, tropoelastin. Tropoelastin molecules bind together to create elastin. Tropoelastin is a water-soluble molecule with a molecular weight of approximately 72,000 Daltons. Multiple tropoelastin molecules covalently bind together with crosslinks to form the protein elastin that is very prevalent in the body. There is only one gene for this molecule
Over 900 extracts were tested and, dill seed was one of a few that contained the Lysyl oxidase-like enzyme so beneficial to elastin. It seems dill extract helps increase expression of enzymes in the skin that generates elastin and help rebuild skin’s structural integrity. Dill may prove to be one of the few plants extracts whose anti-aging abilities influence elastin. In 2006, Cenizo et al. set out to induce elastogenesis (production of elastin) in adult dermal fibroblasts by targeting Lysyl oxidase (LOX) and Lysyl oxidase-like (LOXL) enzymes, which are responsible for elastin crosslinking. LOX and LOXL have been identified as the rate-limiting step in synthesizing mature elastin in adult skin. The expression of LOXL decreases with age. They concluded that LOXL is a suitable target for stimulating elastogenesis, and that dill extract appears to foster such activity.
Sohm, assessed the capacity of dill extract to enhance skin elasticity in vitro and in vivo. He reported that skin firmness and elasticity did indeed improve significantly in subjects treated for 56 days with a 1% topical application of dill extract, compared with subjects treated with placebo. Most volunteers treated with dill extract identified marked enhancements in elasticity, firmness, and jawline slackness. After 84 days, subjects treated with dill also exhibited significantly reduced mean wrinkle area and length compared with those taking the placebo formulation. The greater elasticity might be attributed to increased LOX expression stimulated by dill extract application, though this study did not measure LOX or LOXL.
Several other scientific studies have shown that topical application of formulas with dill may help to reinforce skin elasticity and firmness, thus improving the overall appearance of skin. As a result, the benefits of dill extract are often infused in anti-aging skincare formulas. Furthermore, dill extract is commonly used as a fragrance component in cosmetic and personal care products such as lotions and creams.
Dill seed extract also has the anti-microbial activity. Certain pathogenic microbes cause some skin diseases and destroy the natural beauty proteins that’s elastin and collagen. Due to the anti-microbial activity, dill destroys the micro-organism and thus prevents the destruction of beauty proteins.
References
- Lawless, J. The Encyclopedia of essential oils: the complete guide to the use of aromatic oils in aromatherapy, herbalism, health, and well being. Conari Press (2013)
- Sohm, B. et al. Evaluation of the efficacy of a dill extract in vitro and in vivo. International journal of cosmetic science 33.2, 157-163 (2011)
- Khan, I. and Abourashed, E. Leung’s encyclopedia of common natural ingredients: used in food, drugs and cosmetics. John Wiley & Sons (2011)
- https://www.mdedge.com/dermatology/article/56200/aesthetic-dermatology/dill/page/0/1
- https://en.wikipedia.org/wiki/Elastin#Composition